Oxycontex® 20mg (Taj pharma) 🇮🇳

Mechanism of Action

Oxycodone is a semi-synthetic opioid agonist that binds to mu-opioid receptors in the central nervous system, altering the perception and response to pain. It provides analgesia, sedation, and a sense of well-being.

Therapeutic Indications

Oxycontex® is indicated for the management of moderate to severe chronic pain requiring continuous, around-the-clock opioid therapy when alternative treatment options are inadequate.

Precautions and Side Effects

Common Side Effects:

**Constipation

**Nausea and vomiting

**Drowsiness

**Dizziness

Serious Side Effects:

**Respiratory depression

**Hypotension

**Dependence and withdrawal symptoms

**Adrenal insufficiency

Precautions:

**Use with caution in patients with respiratory disorders, hepatic or renal impairment.

**Avoid concurrent use with other central nervous system depressants.

**Not recommended during pregnancy and lactation unless clearly necessary.

Historical Background

Oxycodone was first developed in Germany in 1916 as a semi-synthetic opioid derived from thebaine. It has been used for pain management since the early 20th century and is available in various formulations worldwide.

Misuse and Abuse Potential

As a Schedule II controlled substance, oxycodone has a high potential for abuse, leading to severe psychological or physical dependence. Misuse can result in overdose and death.

Additional Information

**Pregnancy: Oxycodone crosses the placenta and may cause neonatal opioid withdrawal syndrome. Use only if the potential benefit justifies the potential risk.

**Lactation: Excreted in breast milk; caution is advised.

**Pediatric Use: Safety and efficacy in children have not been established.