component : Prenarpil 0.5 , 1 mg, 2 mg

Prenarpil Consists of active ingredients Clonazepam 2.0

Mechanism of Action

Perindopril is an ACE inhibitor that prevents the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. By inhibiting this process, Perindopril helps relax blood vessels, thereby lowering blood pressure and reducing the workload on the heart.

Indications

Prenarpil is medically indicated for:

**Treatment of hypertension (high blood pressure)

**Management of heart failure

**Prevention of cardiovascular events in patients with coronary artery disease

Precautions and Side Effects

Common Side Effects:

**Dizziness

**Headache

**Dry cough

**Hypotension (low blood pressure)

Serious Side Effects:

**Angioedema (swelling of the face, lips, or throat)

**Hyperkalemia (elevated potassium levels)

**Renal dysfunction

Precautions:

**Pregnancy: Not recommended due to potential fetal harm

**Renal Impairment: Use with caution

**Potassium Levels: Monitor for hyperkalemia

Historical Background

Perindopril was developed in the 1980s and has since been widely adopted for its efficacy in lowering blood pressure and managing chronic heart conditions. It has been studied in large-scale clinical trials and is endorsed by major cardiology guidelines.

Misuse and Abuse Potential

Perindopril does not possess psychoactive or addictive properties and is not known to be used recreationally. However, misuse through overdosage or unsupervised administration can lead to severe hypotension or other complications.